Tumor-related research - 维通达生物技术有限公司

Tumor-related research

We rely on our tumor research platform, professional technical team, and independently developed immunodeficient animal models to have accumulated a series of project experiences in syngeneic tumor transplantation, xenograft tumor transplantation, and establishment of tumor immune dual-humanization over more than twenty years. Weitongda can undertake various tumor efficacy evaluation services, including treatment methods such as cell therapy, gene therapy, and various small and large molecule drugs.

Homologous tumor transplantation
01

Vitalstar has established a comprehensive database of mouse-derived CDX heterotransplantation models in Balb/c, C57, Balb/c nude, and NOD SCID mice, which includes a variety of solid tumors and hematological malignancies. As a Contract Research Organization (CRO), Vitalstar offers a one-stop service ranging from cell culture, tumor modeling, administration, tumor measurement, in vivo imaging, tissue collection, to tumor-related detection and analysis.
Xenogenic tumor transplantation
02

Vitalstar has established an extensive database of PDX and CDX heterotransplantation models in severely immunodeficient mice such as NPG and F344RG, as well as in humanized immune system mice. This database includes a variety of solid tumors and hematological malignancies. As a CRO, Vitalstar offers a comprehensive one-stop service that includes cell culture, tumor modeling, administration, tumor measurement, in vivo imaging, tissue collection, and tumor-related detection and analysis.
Tumor immunity dual humanized
03

The tumor immune humanized mouse models independently developed by Vitalstar provide a powerful tool for cancer research, capable of more accurately simulating the interactions between human tumors and the immune system. These models offer an important platform for the development of immunotherapies, drug screening, and personalized medicine research.
Cell and gene therapy
04

Vitalstar has utilized severely immunodeficient mice and rats to establish a rich database of CDX or PDX allograft models, which have been verified for the efficacy of various cellular and gene therapies. The animals involved include NPG, HSC-NPG, PBMC-NPG, PBMC-DK-NPG, HSC-GM3-NPG mice, as well as F344RG rats.
Efficacy evaluation of small and large molecules
05

Vitalstar's drug efficacy testing services for small and large molecule drugs cover a wide range of types, including monoclonal antibodies, bispecific antibodies, fusion proteins, recombinant proteins, vaccines, cell therapy products, gene therapy products, and stem cell therapies. The animals involved include NPG, HSC-NPG, PBMC-NPG, PBMC-DK-NPG, HSC-GM3-NPG mice, as well as F344RG rats.